Nurofen for Children is generally well tolerated by the majority of people. However, the following adverse effects observed are usually of a mild and transient nature: Stomach discomfort or pain, nausea, gastrointestinal intolerance and bleeding, stomach ulcer, activation of peptic ulcer, black tarry stools, rashes or worsening of asthma, liver and kidney problems (cystitis, haematuria, acute renal failure, interstitial nephritis and nephrotic syndrome), headache, dizziness and hearing disturbance and very rarely skin peeling and easy bruising. Serious skin reaction are also observed, some of them fatal (such as exfoliative dermatitis, Stevens-Johnson Syndrom, toxic epidermal necrolysis), severe hypersensitivity reactions, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), exacerbation of infections in varicella infection, cardiac failure & oedema. Haematopoietic disorders also occur.